• NERC Data Catalogue Service
  •  
  •  
  •  

Antiviral, antibiotics and decongestants in wastewater treatment plants and receiving rivers in the Thames catchment

This dataset contains the concentration of eleven antibiotics (trimethoprim, oxytetracycline, ciprofloxacin, azithromycin, cefotaxime, doxycycline, sulfamethoxazole, erythromycin, clarithromycin, ofloxacin, norfloxacin), three decongestants (naphazoline, oxymetazoline, xylometazoline) and the antiviral drug oseltamivir's active metabolite, oseltamivir carboxylate, measured at 21 locations within the River Thames catchment in England. The measurements were taken weekly during November 2009, once in March 2010 and once in May 2011, with the aim to quantify pharmaceutical usage during the influenza pandemic of 2009 and how this compares to inter-pandemic drug use. River samples were acquired by grab samples in glass jars and analysed by liquid chromatography tandem mass spectrometry (LC MS). Two wastewater treatment plants (WWTPs) in southern England (Benson and Oxford) were also sampled during the peak of the second wave of the 2009 influenza A[H1N1]pdm09 pandemic (10-11 November 2009) and on 15 May 2011 using an automated sampler set to acquired hourly (time proportional) samples from the influent and effluent of the WWTPs. The WWTPs are the source for all the drugs found in the river, hence, these were studied to understand the differential fate of the analytes in the two very different WWTPs. Flows for the WWTP and River sampling locations are presented for each of the sampling times to allow for determining hourly loads for the WWTP and daily loads for the river. Full details about this dataset can be found at https://doi.org/10.5285/8af983e4-e97d-4c07-a34d-753243fa283b

Simple

Date (Publication)
2014-08-01
Date (Creation)
2009-11-03
Identifier
CEH:EIDC: / 1406898956642
Identifier
https://catalogue.ceh.ac.uk/id/8af983e4-e97d-4c07-a34d-753243fa283b
Identifier
doi: / 10.5285/8af983e4-e97d-4c07-a34d-753243fa283b
Other citation details
Singer, A.C., Järhult, J.D., Grabic, R., Khan, G.A., Lindberg, R.H., Fedorova, G., Fick, J., Bowes, M.J., Olsen, B., Söderström, H. (2014). Antiviral, antibiotics and decongestants in wastewater treatment plants and receiving rivers in the Thames catchment. NERC Environmental Information Data Centre 10.5285/8af983e4-e97d-4c07-a34d-753243fa283b
Point of contact
  UK Centre for Ecology & Hydrology - Singer, A.
Author
  Centre for Ecology & Hydrology - Singer, A.C.
https://orcid.org/0000-0003-4705-6063
Author
  Uppsala University - Järhult, J.D.
https://orcid.org/0000-0002-7075-1059
Author
  University of South Bohemia in Ceske Budejovice - Grabic, R.
https://orcid.org/0000-0002-0935-2075
Author
  Umeå University - Khan, G.A.
Author
  Umeå University - Lindberg, R.H.
https://orcid.org/0000-0001-5352-0091
Author
  University of South Bohemia in Ceske Budejovice - Fedorova, G.
https://orcid.org/0000-0001-5492-7459
Author
  Umeå University - Fick, J.
https://orcid.org/0000-0002-3949-7371
Author
  Centre for Ecology & Hydrology - Bowes, M.J.
https://orcid.org/0000-0002-0673-1934
Author
  Uppsala University - Olsen, B.
Author
  Umeå University - Söderström, H.
https://orcid.org/0000-0002-0842-3409
Custodian
  NERC EDS Environmental Information Data Centre
Publisher
  NERC Environmental Information Data Centre
Owner
  UK Centre for Ecology & Hydrology
Maintenance and update frequency
notPlanned Not planned
GEMET - INSPIRE themes, version 1.0
  • Hydrography
Access constraints
otherRestrictions Other restrictions
Other constraints
no limitations
Use constraints
otherRestrictions Other restrictions
Other constraints
This resource is made available under the terms of the Open Government Licence
Use constraints
otherRestrictions Other restrictions
Other constraints
© UK Centre for Ecology & Hydrology
Use constraints
otherRestrictions Other restrictions
Other constraints
If you reuse this data, you should cite: Singer, A.C., Järhult, J.D., Grabic, R., Khan, G.A., Lindberg, R.H., Fedorova, G., Fick, J., Bowes, M.J., Olsen, B., Söderström, H. (2014). Antiviral, antibiotics and decongestants in wastewater treatment plants and receiving rivers in the Thames catchment. NERC Environmental Information Data Centre https://doi.org/10.5285/8af983e4-e97d-4c07-a34d-753243fa283b
Spatial representation type
textTable Text, table
Metadata language
EnglishEnglish
Character set
utf8 UTF8
Topic category
  • Inland waters
Begin date
2009-11-11
End date
2011-05-11
N
S
E
W
thumbnail


Unique resource identifier
OSGB 1936 / British National Grid
Distribution format
  • Comma-separated values (CSV) ()

Distributor
  NERC EDS Environmental Information Data Centre
OnLine resource
Download the data

Download a copy of this data

OnLine resource
Supporting information

Supporting information available to assist in re-use of this dataset.

Hierarchy level
dataset Dataset
Other
dataset

Conformance result

Date (Publication)
2010-12-08
Statement
The sampling of all analytes in the Benson and Oxford WWTP was performed during a 24-hour period spanning 10-11 November 2009. An additional 24-h sampling was initiated on May 15, 2011 from only the Benson WWTP effluent. An automated sampler was used to recover a time-proportional sample (approximately 750 ml) of influent and effluent every hour for 24 hours. Samples were aliquoted into triplicate 50-ml borosilicate glass vials with PTFE-lined caps and immediately stored at -80°C until analysis. Grab samples were acquired from the main river flow at 21 locations within the Thames catchment as part of the CEH Thames Initiative Research Platform on November 3, 11, 17, and 24, 2009, as well as on March 15, 2010 (late-pandemic period) and May 11, 2011 (inter-pandemic period). River flow data was acquired from the National River Flow Archive (http://www.ceh.ac.uk/data/nrfa/) for all locations at the closest gauging station to the sampling site. Samples were transported from the field to the laboratory in amber glass jars (250 ml) within siz hours and transferred into 50-ml borosilicate glass vials with PTFE-lined caps, in triplicate. The samples were stored at -80°C until analysis. An on-line solid phase liquid extraction/liquid chromatography-tandem mass-spectrometry (SPE/LC-MS/MS) method was used to measure the analyte levels in pre-filtered and acidified 1 mL-samples. This on-line SPE/LC-MS/MS method used has 132 been evaluated and described in detail previously: Khan GA, Lindberg R, Grabic R, Fick J (2012) The development and application of a system for simultaneously determining anti-infectives and nasal decongestants using on-line solid- phase extraction and liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal 66: 24-32.
File identifier
8af983e4-e97d-4c07-a34d-753243fa283b XML
Metadata language
EnglishEnglish
Character set
ISO/IEC 8859-1 (also known as Latin 1) 8859 Part 1
Hierarchy level
dataset Dataset
Hierarchy level name
dataset
Date stamp
2025-03-21T13:20:34
Metadata standard name
UK GEMINI
Metadata standard version
2.3
Point of contact
  NERC EDS Environmental Information Data Centre
Lancaster Environment Centre, Library Avenue, Bailrigg , Lancaster , LA1 4AP , UK
https://eidc.ac.uk/
 
 

Overviews

Spatial extent

N
S
E
W
thumbnail


Keywords

GEMET - INSPIRE themes, version 1.0
Hydrography

Provided by

logo

Share on social sites

Access to the portal
Read here the full details and access to the data.

Associated resources

Not available


  •  
  •  
  •