Methodology:

Data was gathered by mining metadata from Trembl database for various biomineralization specific keywords. Example keywords include: Molluscs, shell, bivalve, aragonite, calcite, prismatic, foliated, mantle, mantle edge, central mantle, pallial mantle, etc. Only SMPs uploaded to Uniprot were included in this database. The database only contains SMPs that have been experimentally validated to be present in molluscan shell matrices (based on the publication(s) attached to the UniProtID). Uniprot entries for only mantle specific sequences were not included, since all such sequences were determined to be biomineralization related based on sequence similarity results to the proteins identified in shell matrices, and were not experimentally validated.

Data collection:

Data was collected from Uniprot (https://www.uniprot.org/).

Data quality:

Database is based on uploaded Unioprot IDs entries until JULY 2018. No major publications have since been released that match the criteria to be included in the database. Missing values are only present in the domain columns - A missing value indicates that there were no functional domains detected in the sequence, based on InterproScan results from Interpro databases.